 |
Case Report
A cebocephaly with holoprosencephaly spectrum: Clinical case and literature review
1 Consultant, Department of Otolaryngology, Addis Ababa University School of Medicine, Tikur Anbessa Hospital, Addis Ababa, Ethiopia
2 Resident, Department of Otolaryngology, Addis Ababa University School of medicine, Tikur Anbessa Hospital, Addis Ababa, Ethiopia
Address correspondence to:
Elizabeth T Beyene
Consultant, Department of Otolaryngology, Addis Ababa University School of Medicine, Tikur Anbessa Hospital, Addis Ababa,
Ethiopia
Message to Corresponding Author
Article ID: 100008Z18EB2023
Access full text article on other devices
Access PDF of article on other devices
How to cite this article
Beyene ET, Shiferaw MF, Kahissay AM. A cebocephaly with holoprosencephaly spectrum: Clinical case and literature review. J Case Rep Images Otolaryngol 2023;4(1):1–6.ABSTRACT
Holoprosencephaly is a brain defect resulting from incomplete cleavage of the embryonic forebrain. It includes a wide spectrum of presentations with several forebrain and midfacial malformations of various degrees ranging from mild to severe. Here we describe the presentation of a newborn with semilobar holoprosencephaly with a cebocephaly (single nostril) and review literature regarding the various neuroimaging and craniofacial findings associated with the condition.
Keywords: Congenital facial malformation, Holoprosencephaly, Pyriform aperture stenosis
SUPPORTING INFORMATION
Acknowledgments
The authors would like to thank all individuals who contributed in the preparation of the manuscript.
Author ContributionsElizabeth T Beyene - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Mehret F Shiferaw - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Amanuel M Kahissay - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Elizabeth T Beyene et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
